Figure 5

Lower blood glucose levels in 4- and 8-month-old Cox7rpKO mice versus WT mice during pyruvate tolerance test (PTT). Cox7rpKO and WT mice at 4-month-old and 8-month-old were fasted for 16 h, then injected intraperitoneally with pyruvate (2 g/kg body weight). Blood glucose level (A) and the AUC (B) in PTT at 4-month-old. Blood glucose level (C) and the AUC (D) in PTT at 8-month-old. Data are presented as means ± SEM (n = 4). *P < 0.05, **P < 0.01, using Student’s t test.