Figure 4

Gene expression levels and patterns differ between infection phases, organs, and T. cruzi infecting strains. Gene expression was measured by qRT-PCR in the spleen (A,E,I,M), liver (B,F,J,N), intestine (C,G,K,O), and heart (D,H,L,P). Animals are grouped by strains in acute (A– D) and chronic phases(E–H), and by intestinal (I–L) or cardiac (M–P) damage. Gene expression was normalized to uninfected controls (black lines). Data are presented as the log10 of the group mean (see Tables S1 to S6 for details).