Figure 5
Epileptic seizures are not responsible for the phenotypes in short-term synaptic plasticity in KI mice. (a) The paired-pulse ratio was indistinguishable between saline-injected control mice (open circles:○, n = 8) and those exhibited an epileptic seizure by intraperitoneal administration of pilocarpine (closed circles:●, n = 8) at all inter-pulse intervals. (b) PTP elicited by tetanic stimulation (100 Hz, 1 s) was indistinguishable between pilocarpine-treated (closed circles:●, n = 8) and control mice (open circles:○, n = 8), although the potentiation 2 to 5 min after tetanic stimulation was significantly different between the groups.
