Table 1 Statistical analysis of self-administration data: I. Spout difference.

From: Social learning promotes nicotine self-administration by facilitating the extinction of conditioned aversion in isogenic strains of rats

Strain

Nicotine 15 μg/kg/inf.

Nicotine 30 μg/kg/inf.

n

Df

F

p

n

Df

F

p

BN

5

(1,40)

136.0

<0.001

5

(1,40)

47.5

<0.001

DA

6

(1,50)

75.1

<0.001

6

(1,50)

14.9

<0.001

F344

8

(1,70)

2.0

>0.05

7

(1,60)

15.5

<0.001

LEW

6

(1,50)

66.5

<0.001

7

(1,60)

1.4

>0.05

SHR

7

(1,60)

38.5

<0.001

5

(1,40)

2.0

>0.05

WKY

5

(1,40)

19.7

<0.001

6

(1,50)

1.9

>0.05

FD

6

(1,50)

1.5

>0.05

6

(1,50)

1.0

>0.05

FL

7

(1,60)

1.2

>0.05

8

(1,70)

15.8

<0.001

FS

7

(1,60)

135.9

<0.001

5

(1,40)

26.0

<0.001

LB

6

(1,50)

82.6

<0.001

5

(1,40)

46.9

<0.001

LS

5

(1,60)

148.2

<0.001

9

(1,80)

8.0

<0.01

WL

5

(1,60)

59.1

<0.001

7

(1,60)

46.6

<0.001

  1. Twelve isogenic strains of rats self-administered nicotine (15 or 30 μg/kg/inf, i.v.) for 10 daily 3 h sessions with a flavored cue. A same-sex conspecific consuming the same cue served as a demonstrator to provide an environment for social learning. The number of active vs inactive licks were analyzed using two-way repeated measures ANOVA. The p values that achieved statistical significance (p < 0.05) are highlighted in bold.
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