Figure 1 | Scientific Reports

Figure 1

From: Re-characterization of the Glomerulopathy in CD2AP Deficient Mice by High-Resolution Helium Ion Scanning Microscopy

Figure 1

Analysis of proteinuria and kidney histology. (A) Coomassie blue staining reveals a significant amount of proteinuria of a wide molecular weight range in 6 week-old Cd2ap-KO mice but not in the WT mice. (B) Representative images of H&E staining in WT, 3 week- and 6 week-old Cd2ap-KO kidneys. While there are no obvious abnormalities of the glomerular structure in 3 week-old Cd2ap-KO kidneys compared to WT, nearly half of the glomeruli show segmental or global sclerosis. Moderate tubular atrophy and protein casts (arrow) were also detected in kidney tubules.

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