Figure 2 | Scientific Reports

Figure 2

From: Activated Mesenchymal Stem Cells Interact with Antibiotics and Host Innate Immune Responses to Control Chronic Bacterial Infections

Figure 2

Effects of activated MSC administration on wound healing in mouse chronic infection model. Mice with S. aureus infected mesh implants were treated as described in Fig. 1. At the completion of the study (day 14), mice were euthanized and skin was dissected to reveal the implant site. In (A), representative photograph of a wound treated with antibiotics only, and corresponding representative photomicrographs of H&E sections (B,C) revealing suppurative inflammation at the wound site. In (D) representative photograph of a wound in a mouse treated with activated MSC plus antibiotics, with implanted mesh visible in wound bed. In (E,F) representative photomicrographs of (H&E) sections from a mouse treated with activated MSC plus antibiotics, revealing mild monocytic inflammation.

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