Figure 2

Phylogeny of ArsM As(III) SAM methyltransferases. The phylogenetic tree was constructed using the maximum likelihood program RAxML. The statistical significance of the branch pattern was estimated by conducting 100 bootstrap replications of the original amino acid alignment; bootstraps >50 were shown as blue circle. The detailed trees of each group are provided in Fig. 3, Figure 4–6 The related SAM-dependent mycolic acid cyclopropane synthetase (cmaS) genes were used as outgroup14.