Figure 3 | Scientific Reports

Figure 3

From: Prognostic significance and function of mammalian target of rapamycin in tongue squamous cell carcinoma

Figure 3

mTOR activity involved in cell proliferation of tongue cancer cells. (A) The protein expression levels of total mTOR, and phosphorylated mTOR were demonstrated in SAS and HSC-3 cells transfected with siControl and simTOR by Western blotting. (B and C) The cell growth abilities of siControl and simTOR in both SAS and HSC-3 cells were measured by MTT and BrdU assays. (D) The protein expression levels of total mTOR, and phosphorylated mTOR were detected in SAS and HSC-3 cells treated with everolimus or DMSO by Western blotting. (E and F) the cell growth abilities of both two cells treated with everolimus in a dose-dependent manner were assessed by MTT and BrdU assays. Eve: everolimus. *p < 0.05; **p < 0.01, ***p < 0.001.

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