Figure 1 | Scientific Reports

Figure 1

From: The Mitochondrial-Derived Peptides, HumaninS14G and Small Humanin-like Peptide 2, Exhibit Chaperone-like Activity

Figure 1

Mitochondrial-derived peptides HNG and SHLP2 inhibit IAPP fibrilization. (A and B) Representative ThT kinetics traces of IAPP misfolding in the presence of a) HNG or b) SHLP2. (C) End point analysis of IAPP misfolding by ThT fluorescence at 18 hours. Trend lines are shown for clarity. Concentrations of MDPs used to inhibit IAPP misfolding are given in micromolar below the figure. *p < 0.01. Error bars represent +/− 1 standard deviation from a minimum of 3 experiments.

Back to article page