Figure 4

Local rigid conformation in a deformable loop, low N _eq versus high RMSF. (A) Superimposed RMSF and N _eq values (red and blue curves respectively) from residues N665 to G668, (B) The WebLogo⁴⁹ indicates the frequency of occurrences with respect to the PBs adopted (size of the letter) by a residue in MD simulations. Here, residues V666 to F669 mainly adopted the PBs profile “ehia” corresponding to low N _eq for them. (C) 3D model of the Calf-1 domain and the frame magnified of two adopted by the loop conformations (red and yellow worm-lines) carrying the residue E667 (in blue) that keep a rigid structure relative to the mobile loop.