Table 1 List of PAE-Rβ mutants.

From: PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway

PAE-Rβ mutants

Target protein(s)

Y740/751F

PI3K and NcK

Y763F

SHP2

Y763/1009F

SHP2

Y771F

Ras and GAP

Y775F

Grb2 and Stat

Y775/778F

Grb2 and Stat

Y934F

 

Y1009/1021F

PLCγ and SHP2

  1. List of PAE-Rβ mutants and the signaling protein(s) that their mutated PDGF-Rβ receptor cannot interact with upon receptor activation.