Table 2 Independent Predictors of Percent Change in eGFR at 1-Year Follow-up.

From: Circulating CD40 and sCD40L Predict Changes in Renal Function in Subjects with Chronic Kidney Disease

Predictors

Effect estimate (% change in eGFR) (95% CI)

Odds Ratio (95% CI)

P-value

High sCD40L

−7.57 (−13.60, −1.54)

1.89 (1.13, 3.10)

0.014

Low sCD40R

−6.39 (−12.59, −0.18)

1.71 (1.01, 2.85)

0.044

Systolic BP

−0.20 (−0.36, −0.04)

1.02 (1.00, 1.03)

0.02

  1. Model was adjusted by age, sex, baseline eGFR, systolic blood pressure (SBP), peripheral vascular disease (PVD), diabetes mellitus, primary renal disease, and baseline ACEi/ARB or aspirin use. Odds ratios were calculated for a negative percent change in eGFR at 1-year follow-up. Only significant predictors are shown.
  2. Abbreviations: eGFR, estimated glomerular filtration rate; sCD40L, soluble CD40 ligand; sCD40R, soluble CD40 receptor; BP, blood pressure; and CI, confidence interval.
Back to article page