Figure 8
From: Injectable Phosphorescence-based Oxygen Biosensors Identify Post Ischemic Reactive Hyperoxia
Overview of experimental design. Day 0: bilateral and symmetric subcutaneous implantation of biosensors, with unilateral ligation of femoral vessels on one leg. A similar scheme without the surgery was performed for subsequent measurement days. Days 28 & 84: simultaneous real-time measurement with three techniques (biosensor, NIR spectroscopy, laser Doppler) while the rats were subjected to a series of hypoxic challenges and tourniquet application as illustrated. Illustrated by Lauren Halligan, MSMI; copyright Duke University; with permission under a CC-BY 4.0 license.
