Figure 1 | Scientific Reports

Figure 1

From: Characterization of the Mollusc RIG-I/MAVS Pathway Reveals an Archaic Antiviral Signalling Framework in Invertebrates

Figure 1

Response of oyster larvae to OsHV-1 infection. (A) Ratio of RNA-seq reads mapping to the OsHV-1 and Vibrio genomes; the number of oyster larvae is also shown. Sampling times of oyster larvae and abbreviations for developmental stages are the same as those in Table S12 of ref. 31. The abbreviations are: E: Egg; TC: Two cells; FC: Four cells; EM: Early morula; M: Morula; B: Blastula; RM: Rotary movement; FS: Free swimming; EG: Early gastrula; G: Gastrula; T: Trochophore; ED: Early D-shape larvae; D: D-shape larvae; EU: Early umbo larva; U: Umbo larva; LU: Later umbo larva; P: Pediveliger. S: Spat. (B) Expression of RIG-I like receptors (RLRs) in oyster larvae infected with OsHV-1. Cg24392, Cg14034, Cg22973, and Cg03083 are RLRs with CARD domains, and the remaining genes do not possess CARD domains. (C and D) Expression of genes involved in the RLR signalling pathway, including TRAF2 (Cg08964), TRAF3 (Cg23158), TRAF6 (Cg10206), three MITA (transmembrane protein 173) genes (Cg06439, Cg03079, and Cg22970), and three IRF genes (Cg21170, Cg21171, and Cg03270).

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