Table 1 Hemodynamic and neurohormonal changes in an ovine model of rapid pacing-induced heart failure and recovery.
From: Identification of novel microRNAs in the sheep heart and their regulation in heart failure
| ย | Control (nโ=โ13) | HF (nโ=โ6) | HF-R (nโ=โ8) |
|---|---|---|---|
Hemodynamic Measurements | |||
Heart Rate (bpm) | 80โยฑโ4 | 218โยฑโ2*** | 84โยฑโ5โ โ โ |
Cardiac Output (L/min) | 7.13โยฑโ0.22 | 2.93โยฑโ0.13*** | 7.11โยฑโ0.29โ โ โ |
Mean Blood Pressure (mm Hg) | 101.0โยฑโ2.2 | 71.1โยฑโ2.8*** | 87.5โยฑโ3.9*โ โ |
Atrial Pressure (mm Hg) | 5.00โยฑโ0.71 | 28.0โยฑโ0.88*** | 5.88โยฑโ0.50โ โ โ |
Neurohumoral Measurements | |||
ANP (pmol/L) | 16.1โยฑโ3.9 | 297.3โยฑโ26.5*** | 23.9โยฑโ2.0*โ โ โ |
BNP (pmol/L) | 2.85โยฑโ0.75 | 55.3โยฑโ9.33*** | 2.6โยฑโ0.46โ โ |
