Figure 4
Diagnostic value of the three candidate genes in lung cancer by ROC curves analysis. (A) NEK2 (B) DLGAP5 (C) ECT2. The four datasets are marked in the figures. The red line is GSE19188, the blue line is GSE18842, the green line is GSE40791, and the black line is TCGA datasets. For the ROC curve, the comparisions between model with the target gene (Model 1) and the model without the target gene (Model 2) was performed. The Model 1 (red line) includes age, gender, smoking status, clinical stage and the target gene. The Model 2 (green line) without the target gene. (D) NEK2. AUCModel 1 = 0.971 (P-value <0.001), AUC Model 2 = 0.556 (P-value = 0.231). (E) DLGAP5. AUCModel 1 = 0.977 (P-value <0.001), AUC Model 2 = 0.556 (P-value = 0.231). (F) ECT2. AUCModel 1 = 0.968 (P-value <0.001), AUC Model 2 = 0.556 (P-value = 0.231).
