Figure 4

Small-animal PET/MR brain images of [18F]FE@SNAP. Exemplary small-animal PET/MR images of representative coronal (left), horizontal (centre) and sagittal (right) planes of a rat brain with [18F]FE@SNAP before and after administration of 15 mg/kg (±)-SNAP-7941 (a) and with [18F]FE@SNAP before and after administration of the corresponding vehicle (b). PET data are contributed to summation images from 0–20 minutes (before displacement) and from 20–60 minutes (after displacement). Anatomical structures are indicated by arrows (LV = lateral ventricle; LLV = left lateral ventricle; 3V = third ventricle; 4V = fourth ventricle).