Table 2 The association between alcohol drinking and risk of head and neck cancer overall and by sites.
From: Investigating the Association between Alcohol and Risk of Head and Neck Cancer in Taiwan
Alcohol drinkinga | Controls n (%) | Head and neck cancer n (%) | OR (95% CI)b | Oral cavity n (%) | OR (95% CI)b | Oro- pharynx n (%) | OR (95% CI)b | Hypo- pharynx n (%) | OR (95% CI)b | Larynx n (%) | OR (95% CI)b |
|---|---|---|---|---|---|---|---|---|---|---|---|
Never + occasional | 517 (55.0) | 263 (32.4) | Referent | 195 (38.3) | Referent | 29 (24.6) | Referent | 4 (4.5) | Referent | 35 (36.8) | Referent |
Former regular | 109 (11.6) | 111 (13.7) | 1.14 (0.80–1.62) | 61 (12.0) | 0.77 (0.51–1.17) | 20 (16.9) | 2.83 (1.39–5.76) | 19 (21.3) | 14.02 (4.38–44.85) | 11 (11.6) | 0.86 (0.40–1.85) |
Current regular | 314 (33.4) | 437 (53.9) | 1.81 (1.41–2.34) | 253 (49.7) | 1.29 (0.97–1.73) | 69 (58.5) | 4.23 (2.38–7.52) | 66 (74.2) | 21.55 (7.36–63.15) | 49 (51.6) | 1.84 (1.09–3.11) |
Ever regular (Former regular + current regular) | 423 (45.0) | 548 (67.6) | 1.62 (1.28–2.06) | 314 (61.7) | 1.14 (0.87–1.50) | 89 (75.4) | 3.80 (2.19–6.60) | 85 (95.5) | 19.17 (6.64–55.39) | 60 (63.2) | 1.51 (0.92–2.48) |
Frequency | |||||||||||
Never | 454 (48.3) | 238 (29.3) | Referent | 178 (35.0) | Referent | 26 (22.0) | Referent | 4 (4.5) | Referent | 30 (31.6) | Referent |
Monthly | 63 (6.7) | 25 (3.1) | 1.05 (0.61–1.81) | 17 (3.3) | 0.92 (0.49–1.73) | 3 (2.6) | 1.31 (0.36–4.73) | 0 | — | 5 (5.2) | 1.81 (0.64–5.15) |
Weekly | 126 (13.4) | 83 (10.2) | 1.32 (0.92–1.90) | 49 (9.6) | 0.94 (0.61–1.46) | 13 (11.0) | 2.92 (1.35–6.34) | 12 (13.5) | 13.47 (3.98–45.63) | 9 (9.5) | 1.05 (0.46–2.40) |
Daily | 291 (31.0) | 447 (55.1) | 1.72 (1.32–2.23) | 250 (49.1) | 1.15 (0.85–1.55) | 74 (62.7) | 4.38 (2.39–8.06) | 73 (82.0) | 18.83 (6.45–54.99) | 50 (52.6) | 1.91 (1.10–3.30) |
Unknown | 6 (0.6) | 18 (2.2) | — | 15 (3.0) | — | 2 (1.7) | — | 0 (0.0) | — | 1 (1.1) | — |
Amount | |||||||||||
Never | 435 (49.9) | 222 (30.1) | Referent | 165 (36.0) | Referent | 24 (21.4) | Referent | 4 (5.0) | Referent | 29 (33.0) | Referent |
Light | 192 (22.0) | 105 (14.3) | 1.08 (0.77–1.50) | 68 (14.9) | 0.85 (0.58–1.25) | 13 (11.6) | 1.90 (0.86–4.19) | 13 (16.5) | 6.63 (2.03–21.63) | 11 (12.5) | 0.77 (0.36–1.66) |
Moderate | 103 (11.8) | 109 (14.8) | 1.47 (1.02–2.11) | 66 (14.4) | 1.13 (0.74–1.72) | 17 (15.2) | 4.04 (1.86–8.81) | 19 (24.1) | 14.54 (4.55–46.51) | 7 (7.9) | 0.86 (0.35–2.15) |
Heavy | 132 (15.1) | 283 (38.4) | 2.21 (1.61–3.02) | 144 (31.4) | 1.25 (0.87–1.80) | 56 (50.0) | 7.86 (3.95–15.63) | 43 (54.4) | 20.36 (6.75–61.36) | 40 (45.5) | 3.44 (1.85–6.41) |
Unknown | 10 (1.2) | 18 (2.4) | — | 15 (3.3) | — | 2 (1.8) | — | 0 (0.0) | — | 1 (1.1) | — |
Every 10 grams/day of ethanol |  |  | 1.04 (1.02–1.05) |  | 1.01 (1.00–1.03) |  | 1.06 (1.03–1.09) |  | 1.07 (1.03–1.10) |  | 1.05 (1.02–1.08) |
