Figure 1 | Scientific Reports

Figure 1

From: Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin

Figure 1

Sch B synergistically enhances cytotoxicity of DOX in DOX-resistant cancer cells. (A) Chemical structure of Sch B. MCF-7 (B), MCF-7/ADR (C), A2780 (D) and A2780/DOX (E) cells were treated with DOX for 48 h with or without the pretreatment of Sch B (10 μM) for 12 h and the cell viability was determined by MTT assay. All values represent mean ± SEM. *P < 0.05 and **P < 0.01.

Back to article page