Figure 4

(A) Structure based sequence alignment between the protease domain from SpWss1 (PDB: 5JIG) and ScWss1 (PDB: 5XBN), performed using Clustalw (version 2.0) and Espript 3²⁶. The conserved residues are boxed in blue. Identical conserved and low conserved residues are highlighted in red background and red letters, respectively. (B) Conserved residues are mapped onto the ScWss1^21-148 surface. Identical conserved residues, low conserved residues, and the most variable residues are shown in red, pink, and cyan, respectively. The zinc ion is shown in green sphere.