Table 1 Demographic and Clinical Features of 17 Patients with BO.
From: Mycoplasma pneumoniae–Associated Bronchiolitis Obliterans Following Acute Bronchiolitis
Age at diagnosis Gender | Clinical presentation | Imaging findings | Lung function(%) | Severity | Asthma, other personal atopic disease | Allergen | Family atopic disease | Follow up | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FEV1 | FVC | FEF75% | |||||||||||||
initial | latest | Increase% after salbutamol | initial | latest | initial | latest | Time (yrs) | Outcome | |||||||
8yr 2mo M | Shortness of breath on exertion for 5mo after bronchiolitis | Mosaic attenuation | 70.5 | 73.7 | 16.8 | 89.5 | 90.3 | 40.9 | 44.0 | Mild | Asthma & AR before bronchiolitis | Dog fur, mould | Grand- father AR | 1.0 | Symptom and lung function improvement |
3yr 4mo M | Wheezing on exertion for 2mo after bronchiolitis | Mosaic attenuation | 71.7 | 74 | 16.5 | 88.9 | 92 | 30.4 | 34.8 | Mild | Eczema&AR before bronchiolitis, Asthma after BO | Mould | Mother AR and urticaria | 3.0 | Symptom and lung function improvement |
7yrs M | Wheezing on exertion for 2mo after bronchiolitis | Mosaic attenuation | 72 | 80 | 25.6 | 98.2 | 100 | 44.6 | 50.5 | Mild | Simultaneous Asthma &BO | Dust mite | Mother AR | 1.5 | Symptom and lung function improvement |
4yrs 9mo M | Wheezing for 6mo after bronchiolitis | Mosaic attenuation | 72.8 | 75.6 | 43 | 88.9 | 90 | 40.2 | 44 | Mild | Eczema before bronchiolitis,Asthma after bronchiolitis | Dust mite, milk | Mother AR | 2.0 | Symptom and lung function improvement |
7yrs 6mo M | Tachypnoea&wheezing for 6mo after bronchiolitis | Mosaic attenuation, bronchi-ectasis, air-trapping | 63.6 | 71.7 | 13.2 | 85.2 | 96.2 | 18.4 | 24.4 | Moderate | AR& atopic dermatitis, Asthma after bronchiolitis | Dust mite, pollen | Grand- father Asthma | 1.5 | Symptom and lung function improvement |
4yrs F | Wheezing &dyspnoea for 2mo during & after bronchiolitis | Mosaic attenuation, bronchi-ectasis, air-trapping | 50.9 | 63.0 | 22.1 | 81.0 | 87.3 | 15.6 | 24.4 | Moderate | Eczema, Asthma after BO | Sea food | Father AR | 5.5 | Symptom and lung function improvement |
3yrs 4mo M | Wheezing for 2mo during & after bronchiolitis | Mosaic attenuation, bronchi-ectasis, air-trapping | 53 | 62.6 | 25 | 82.0 | 86.0 | 18.6 | 25 | Moderate | Asthma &eczema before bronchiolitis | Mould, egg | Mother Atopic dermatitis | 5.0 | Symptom and lung function improvement |
6yrs 4mo F | Wheezing &tachypnoea for 3mo after bronchiolitis | Mosaic attenuation, bronchi-ectasis, air-trapping | 66.3 | 68.4 | 28.8 | 81.2 | 85.4 | 26.4 | 35.1 | Moderate | AR &Asthma after BO | Shrimp | Mother & Father AR | 4.0 | Symptom and lung function improvement |
5yrs 6mo M | Dyspnoeaon exertion for 5mo after bronchiolitis | Mosaic attenuation, air-trapping, left lung hyperlucent | 57.3 | 58.9 | 2.8 | 84.6 | 85.5 | 18.3 | 19.1 | Moderate | Asthma after bronchiolitis | Cock-roach, seafood | Mother Urticaria, Uncle Asthma | 4.0 | Symptom improvement, lung function no change |
4yrs 4mo M | Tachypnoea on exercise for 6mo after bronchiolitis | Mosaic attenuation, left lung collapse | 69.8 | 75 | 34 | 83 | 88 | 31.0 | 36 | Moderate | AR before bronchiolitis, Asthma after BO | Dust mite | Father AR | 2.0 | Symptom and lung function improvement |
7yrs 4mo M | Wheezing &dyspnoea for 6mo after bronchiolitis | Mosaic attenuation, bronchi- ectasis,air-trapping, left lung hyperlucent | 37.4 | 35.1 | 32.5 | 55.2 | 55 | 11.9 | 10.9 | Severe | Asthma before bronchiolitis | Dust mite | Mother Urticaria | 1.0 | Symptom improvement, lung function no change |
3yrs 6mo F | Wheezing&dyspnoea for 1.5mo during and after bronchiolitis | Mosaic attenuation, central bronchi ectasis, emphysema | 64.3 | 38 | 43 | 69.8 | 61.1 | 27.8 | 11.8 | Severe | Simultaneou-s Asthma & BO, Urticaria& AR | Dust mite, pollen | Mother, aunt &grand- father AR &urticaria | 5.0 | Symptoms and lung function worse |
4yrs 9mo F | Wheezing &dyspnoea for 8moduring &after bronchiolitis | Mosaic attenuation, bronchi- ectasis, air-trapping, left lung hyperlucent | 48.4 | 50.8 | 16.2 | 77.3 | 78.2 | 14.6 | 13.9 | Severe | Asthma after bronchiolitis | Dust mite, pollen, cat fur | Mother AR &asthma, Grand-father Asthma | 6.0 | Symptom improvement, lung function no change |
5yrs M | Wheezing &dyspnoea for 7mo during & after bronchiolitis | Mosaic attenuation, central bronchi- ectasis, emphysema | 48.1 | 33.8 | 81.8 | 77.3 | 62 | 15.7 | 13.8 | Severe | Asthma before bronchiolitis | Sea food, dust mite | Mother AR | 4.5 | Symptoms and lung function worse |
4yrs 6mo M | Wheezing &dyspnoea for 4mo during & after bronchiolitis | Mosaic attenuation, central bronchi-ectasis, emphysema | 28.8 | 25.7 | 55.2 | 50.8 | 58 | 15.8 | 8.6 | Severe | Eczema, Asthma after BO | Mould, Dust mite | Father AR | 3.5 | Symptoms and lung function worse |
12yrs 8mo F | Dyspnoea for 4mo after bronchiolitis | Mosaic attenuation, central bronchi- ectasis, emphysema | 17 | 18 | 9.8 | 49 | 49 | 10 | 8 | Severe | Skin urticaria | Mould | Mother AR | 1.0 | Symptoms and lung function no change |
9yr 2mo M | Wheezing on exertion for 3mo after bronchiolitis | Mosaic attenuation | 74.3 | 75 | 1.9 | 78.5 | 80.7 | 40.5 | 38.9 | Mild | Eczema | Dust mite | Father AR | 1.0 | Symptom improvement, lung function no change |
