Table 2 Distributions of genotypes and alleles frequencies of five variants in ET patients and healthy controls.
Variants | Genotypes/alleles | ET patients (n = 218) (%) | HCs (n = 315) (%) | p OR(95%CI) |
|---|---|---|---|---|
rs10937625 | CC | 3(1.4) | 15(4.8) | 0.037 0.69[0.48–0.98] |
TC | 52(23.9) | 91(28.9) | ||
TT | 163(74.8) | 209(66.3) | ||
C | 58(13.3) | 121(19.2) | 0.033 0.82[0.69–0.99] | |
T | 378(86.7) | 509(80.8) | ||
rs17590046 | CC | 2(0.9) | 4(1.3) | 0.794 1.06[0.68–1.67] |
TC | 33(15.1) | 43(13.7) | ||
TT | 183(83.9) | 268(85.1) | ||
C | 37(8.5) | 51(8.1) | 0.791 1.03[0.82–1.30] | |
T | 399 (91.5) | 579(91.9) | ||
rs12764057 | GG | 14(6.4) | 18(5.7) | 0.337 1.16[0.86–1.55] |
TG | 88(40.4) | 115(36.5) | ||
TT | 116(53.2) | 182(57.8) | ||
G | 116(26.6) | 151(24.0) | 0.337 1.08[0.93–1.25] | |
T | 320(73.4) | 479(76.0) | ||
rs10822974 | AA | 36(16.5) | 79(25.1) | 0.102 0.81[0.62–1.04] |
GA | 116(53.2) | 148(47.0) | ||
GG | 66(30.3) | 88(27.9) | ||
A | 188(43.1) | 306(48.6) | 0.100 0.90[0.79–1.02] | |
G | 248(56.9) | 324(51.4) | ||
rs7903491 | GG | 44(20.2) | 46(14.6) | 0.030 1.34[1.03–1.74] |
AG | 105(48.2) | 148(47.0) | ||
AA | 69(31.7) | 121(38.4) | ||
G | 193(44.3) | 240(38.1) | 0.029 1.16[1.02–1.32] | |
A | 243(55.7) | 390(61.9) |
