Figure 3 | Scientific Reports

Figure 3

From: Human cytomegalovirus escapes immune recognition by NK cells through the downregulation of B7-H6 by the viral genes US18 and US20

Figure 3

Exogenous overexpression of US18 and US20 is sufficient for reducing B7-H6 surface expression. (A) FACS staining for B7-H6 on ARPE19 cells overexpressing HCMV US17, US18, US19 or US20, as presented above the relevant graphs. Histogram colors are as depicted in the figure legend. One representative experiment out of ten is presented. (B) Quantification of the results presented in A. Averages of four to ten experiments are presented. Error bars in B represent standard error of the mean. An ANOVA test was performed in order to evaluate significance. *p-value < 0.05. N.S. = non-significant differences.

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