Figure 5

PCR validation of changes in CARTpt mRNA expression in the dorsal striatum after a month withdrawal from methamphetamine SA and footshocks. We conducted quantitative PCR using individual RNA from the dorsal striatum (a) and NAc (b) of rats. The shock-resistant rats showed significant increases in CARTpt in the dorsal striatum (a) but not in the NAc (b). Values are means ± SEM fold changes relative to the control group. Key to statistics: *p < 0.05, in comparison to the control group; ##p < 0.01, in comparison to YSR rats; ^^p < 0.01, in comparison to the YSS group; $$p < 0.01 in comparison to the SR group.