Table 1 In vitro and in vivo ER50s of horse anti-N. kaouthia sera in neutralizing N. kaouthia venom.

From: A novel in vitro potency assay of antisera against Thai Naja kaouthia based on nicotinic acetylcholine receptor binding

Horse

In vitro ER50 ± S.D. (µg venom/µl antiserum)

In vivo ER50 (mg venom/ml antiserum)

Nk-A

0.8598 ± 0.1089

0.36 (0.24–0.54)

Nk-B

3.8693 ± 0.2887

1.57 (1.05–2.36)

Nk-C

1.2039 ± 0.2074

0.69 (0.46–1.03)

Nk-D

1.0055 ± 0.1368

0.51 (0.34–0.76)

Nk-E

0.7526 ± 0.2438

0.32 (0.21–0.48)

Nk-F

0.5911 ± 0.0433

0.31 (0.21–0.47)

Nk-G

0.6456 ± 0.0727

0.36 (0.24–0.53)

Nk-H

0.2921 ± 0.0564

0.18 (0.12–0.27)

Nk-I

0.4060 ± 0.1322

0.17 (0.11–0.26)

Nk-J

0.1307 ± 0.0467

0.14 (0.09–0.20)

Nk-K

0.1748 ± 0.0031

0.15 (0.10–0.23)

Nk-L

0.1712 ± 0.0530

0.17 (0.12–0.26)

  1. For each batch of antiserum, the in vitro ER50 was mean ± S.D. from 4 determinations while the in vivo ER50 was median ± 95% C.I. (C.I. = confidence level).
Back to article page