Table 1 Characteristics of patients with type 2 diabetes with or without diabetic foot disease.

From: Sarcopenia is independently associated with diabetic foot disease

 

DFD (N = 120)

non-DFD (N = 985)

P value

Male/Female (person)

67/53

565/420

0.845

Age (year)

66.84 ± 11.18

64.35 ± 9.32

0.007

Duration of Diabetes (year)

9(5,15)

8(4,13)

0.086

History of Hypertension (%)

63.1

58.1

0.361

History of Smoking (%)

53.70

39.10

0.032

BMI (kg/m2)

24.03 ± 3.55

24.85 ± 3.23

0.010

Waist Circumference (cm)

94.9 ± 9.74

94.85 ± 9.12

0.953

Hemoglobin (g/L)

119.55 ± 20.68

134.09 ± 18.19

<0.001

White Blood Cell (*109/L)

8.14 ± 3.81

6.34 ± 1.44

<0.001

Neutrophil (*109/L)

6.11 ± 3.83

4.07 ± 1.22

<0.001

Total Cholesterol (mmol/L)

4.02 ± 1.16

4.25 ± 1.13

0.040

Triglyceride (mmol/L)

1.37 ± 0.70

1.87 ± 1.63

0.001

HDL-c (mmol/L)

1.11 ± 0.38

1.15 ± 0.37

0.334

LDL-c (mmol/L)

2.50 ± 1.02

2.58 ± 0.94

0.413

hs-CRP (mg/L)

6.92 (2.34,20.00)

0.84 (0.44,1.79)

<0.001

HbA1c (%)

9.38 ± 2.42

8.43 ± 2.23

<0.001

UACR (mg/g)

35.7 (10.35,158.95)

12.25 (4.2,50.6)

0.001

Creatinine (μmol/L)

76.37 (59.25,97.51)

71.13 (59.02,87.56)

<0.001

Uric Acid (μmol/L)

302.87 ± 114.49

312.88 ± 88.9

0.275

Ankle Brachial Index

1.03 (0.96,1.18)

1.16 (1.12,1.21)

<0.001

Chronic Diabetic Complications

Diabetic Retinopathy (%)

47.9

26.7

<0.001

Diabetic Peripheral Neuropathy (%)

81.5

70.9

0.012

Diabetic Kidney Disease (%)

42.7

31.9

0.047

Coronary Heart Disease (%)

15.1

15.8

1.000

PAD (%)

24.4

1.3

<0.001

Anti-diabetic and Anti-hypertensive Medications

Metformin (%)

53.1

68.9

0.002

Insulin Secretagogues (%)

15.3

33.8

<0.001

Acarbose (%)

22.9

26.9

0.341

Insulin (%)

73.3

62.7

0.049

ACEI/ARB (%)

33.1

52.9

<0.001

CCB (%)

33.8

32.8

1.000

Diuretic (%)

12.2

4.6

0.004

  1. Data are presented with mean ± SD, median (interquartile range), or %. BMI: body mass index, HDL-c: high density lipoprotein cholesterol, LDL-c: low density lipoprotein cholesterol, hs-CRP: high-sensitivity c-reactive protein, UACR: urinary albumin-to-creatinine ratio, HbA1c: glycosylated hemoglobin, PAD: peripheral arterial disease, ACEI: angiotensin-converting enzyme inhibitors, ARB: angiotensin receptor blocker, CCB: calcium channel blocker.