Table 2 Characteristics of ARI patients positive for RSV in comparison to ARI patients negative for RSV.
Characteristics | RSV-positive n (%) | RSV-negative n (%) | OR (95% CI) | p-value |
---|---|---|---|---|
Number of patients | 157 (41.0) | 226 (59.0) | ||
Demographics | ||||
Age (months), median (IQR) | 11 (4–18) | 14 (6–27) | ||
Age groups | ||||
Less than 1-month-old | 10 (6.4) | 4 (1.8) | reference | |
1 to less than 3-month-old | 16 (10.2) | 26 (11.5) | 0.2 (0.06–0.9) | 0.061 |
3 –month-old to less than 1-year-old | 56 (35.7) | 65 (28.8) | 0.3 (0.1–1.1) | 0.09 |
1 to less than 2-year-old | 56 (35.7) | 63 (27.9) | 0.3 (0.1–1.2) | 0.09 |
2 to less than 3-year-old | 16 (10.2) | 33 (14.6) | 0.2 (0.05–0.7) | 0.013 |
3 to less than 4-year-old | 3 (1.9) | 24 (10.6) | 0.05 (0.01–0.3) | <0.001 |
4 to less than 5-year-old | 0 (0.0) | 11 (4.9) | NA | <0.001 |
Gender (Male) | 94 (59.9) | 125 (55.3) | 1.2 (0.7–1.8) | 0.217 |
Birth weight (g), median (IQR) | 3,100 (2,700–3,400) | 3,000 (2,700–3,300) | ||
Low birth weight 347¥ | 17 (12.1) | 29 (14.0) | 0.8 (0.4–1.6) | 0.369 |
Wards | ||||
ICU | 27 (17.2) | 31 (13.7) | 1.3 (0.7–2.2) | 0.214 |
Paediatric Infectious Disease | 17 (10.8) | 41 (18.1) | 0.5 (0.3–1.0) | 0.033 |
General Paediatric | 113 (72.0) | 154 (68.1) | 1.2 (0.7–1.8) | 0.246 |
Season (Wet season*) | 144 (97.1) | 112 (49.6) | 11.2 (6.0–21.0) | <0.001 |
PVC 13 received268♯ | 68 (57.1) | 75 (50.3) | 1.3 (0.8–2.0) | 0.268 |
Clinical presentation | ||||
Duration of illness prior to hospitalization (day), median (IQR) | 4 (3–5) | 3 (2–5) | ||
Fever documented at enrolment381 | 94 (60.6) | 141 (62.4) | 0.9 (0.6–1.4) | 0.406 |
Cough381 | 155 (99.4) | 213 (94.7) | 8.7 (1.1–67.9) | 0.010 |
Difficulty breathing375 | 134 (87.0) | 141 (63.8) | 3.8 (2.2–6.5) | <0.001 |
Coryza380 | 149 (95.5) | 190 (84.8) | 3.8 (1.6–8.8) | 0.001 |
Diarrhea372 | 75 (48.4) | 80 (36.9) | 1.6 (1.1–2.4) | 0.017 |
Conjunctival suffusion361 | 1 (0.7) | 11 (5.1) | 0.1 (0.02–0.9) | 0.016 |
Convulsions378 | 6 (3.9) | 34 (15.2) | 0.2 (0.09–0.5) | <0.001 |
Rigors328 | 6 (4.7) | 28 (13.9) | 0.3 (0.1–0.8) | 0.005 |
Vomiting374 | 93 (60.8) | 115 (52.0) | 1.4 (0.9–2.2) | 0.058 |
Physical examination | ||||
Chest indrawing378 | 115 (74.2) | 101 (45.3) | 3.5 (2.2–5.4) | <0.001 |
Nasal flaring371 | 43 (28.7) | 43 (19.5) | 1.7 (1.02–2.7) | 0.027 |
Lymphadenopathy359 | 2 (1.3) | 19 (9.0) | 0.1 (0.03–0.6 | 0.001 |
Abnormal pulmonary auscultation366 | 137 (91.3) | 121 (56.0) | 8.3 (4.4–15.5) | <0.001 |
Tachypnea364 | 89 (58.9) | 82 (38.55) | 2.3 (1.5–3.5) | <0.001 |
Oxygen saturation<90% in room air342 | 17 (11.5) | 30 (15.5) | 0.7 (0.4–1.3) | 0.184 |
Rashes366 | 8 (5.4) | 16 (7.4) | 0.7 (0.3–1.7) | 0.296 |
Respiratory distress367 | 48 (32.7) | 60 (27.3) | 1.3 (0.8–2.0) | 0.161 |
Central cyanosis372 | 20 (13.2) | 26 (11.8) | 1.1 (0.6–2.1) | 0.393 |
Wheeze369 | 51 (33.6) | 62 (28.6) | 1.3 (0.8–1.9) | 0.182 |
Stridor365 | 3 (2.0) | 13 (6.0) | 0.3 (0.09–1.1) | 0.053 |
Grunting369 | 5 (3.4) | 13 (5.9) | 0.6 (0.2–1.6) | 0.193 |
Inability to drink368 | 17 (11.3) | 28 (12.9) | 0.9 (0.5–1.6) | 0.380 |
Prostration or lethargy368 | 9 (6.0) | 18 (8.3) | 0.7 (0.3–1.6) | 0.263 |
Outcomes | ||||
Pneumonia | 132 (84.1) | 145 (64.2) | 2.9 (1.8–4.9) | <0.001 |
Severe pneumonia | 46 (29.3) | 92 (40.7) | 0.6 (0.4–0.9) | 0.014 |
Length of stay ≤ 5 days 376 | 132 (85.2) | 173 (78.3) | 1.6 (0.9–2.8) | 0.060 |
Supplementary oxygen used378 | 29 (18.7) | 40 (17.9) | 1.1 (0.6–1.8) | 0.476 |
Death | 2 (1.3) | 3 (1.4) | 0.9 (0.2–5.8) | 0.666 |
Detection of: | ||||
S. pneumoniae | 98 (62.4) | 115 (50.9) | 1.6 (1.1–2.4) | 0.016 |
H. influenzae | 84 (53.5) | 120 (53.1) | 1.0 (0.7–1.5) | 0.510 |
Influenzavirus | 1 (0.6) | 28 (12.4) | 0.05 (0.01–0.3) | <0.001 |
Human parainfluenza virus | 3 (1.9) | 34 (15.0) | 0.1 (0.03–0.4) | <0.001 |
Human metapneumovirus | 0 (0.0) | 6 (2.7) | NA | 0.041 |
Human adenovirus | 6 (3.8) | 22 (9.7) | 0.4 (0.1–0.9) | 0.021 |
Human rhinovirus | 12 (7.6) | 58 (25.7) | 0.2 (0.1–0.5) | <0.001 |