Table 2 Demographic information of subjects enrolled in this study. The concentration of total tau protein, ϕtau-IMR was detected using IMR. The age and ϕtau-IMR are presented in the form of the mean value ± standard deviation. The standard deviation is attributed to the variations among subjects.

From: Analytical performance of reagent for assaying tau protein in human plasma and feasibility study screening neurodegenerative diseases

Group

Numbers

Age (years)

ϕtau-IMR (pg/ml)

ApoEε4 positive&

Healthy controls

66

64.6 ± 8.6

13.37 ± 7.77

25.0%

MCI due to AD+

24

71.0 ± 10.3

33.33 ± 7.77

36.3%

AD++

29

72.2 ± 9.9

55.44 ± 22.45

52.9%

PD$

41

67.1 ± 13.5

26.20 ± 8.37

—

FTD^

26

62.1 ± 9.2

41.28 ± 20.13

—

VD#

29

78.3 ± 4.4

19.96 ± 9.95

—

  1. +MCI due to AD: mild cognitive impairment due to Alzheimer’s disease.
  2. ++AD: Alzheimer’s disease.
  3. $PD: Parkinson’s disease.
  4. ^FTD: frontal temporal dementia.
  5. #VD: vascular dementia.
  6. &The analysis of ApoEε4 allele was performed only for healthy controls and patients with MCI due to AD and AD.
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