Table 1 Summary of PamGene IPA analysis.
From: Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL
Top Canonical Pathway | p-value |
PTEN Signaling | 1.06E-04 |
Axonal Guidance Signaling | 1.8E-04 |
Semaphorin Signaling in Neurons | 9.7E-04 |
GDNF Family Ligand-receptor Interactions | 1.29E-03 |
STAT3 Pathway | 1.44E-03 |
Top Diseases and Bio Functions | |
Diseases and Disorders | p-value |
Cancer | 2.06E-03 |
Respiratory Disease | 2.06E-03 |
Molecular and Cellular functions | p-value |
Cell Cycle | 1.03E-03 |
Cell Death and Survival | 2.06E-03 |
Cellular Compromise | 2.06E-03 |
Cellular Response to Therapeutics | 2.06E-03 |
Cellular Development | 1.23E-02 |
Top Networks | |
Associated Network Function | Score* |
Carbohydrate metabolism, Cellular Function and Maintenance, Cell-To-Cell Signaling and Interaction | 2 |
Cell Morphology, Hematological System Development and Function, Inflammatory Response | 2 |
Cellular Movement, Cell Death and Survival, Cancer | 2 |
Cell Cycle, DNA Replication, Recombination, and Repair, Cancer | 1 |
