Table 1 Performance of CUBIC-based lymph nodes metastasis screening.

From: CUBIC pathology: three-dimensional imaging for pathological diagnosis

  

3D → sectioning

Positive (n = 27)

Negative (n = 47)

Routine method

Positive (n = 23)

23

0

Negative (n = 51)

4

47

  1. 74 lymph nodes were selected from the cases in which at least one lymph node, among all regional lymph nodes for each case, was diagnosed as positive for metastasis (>pT1) by the routine diagnosis method. Four lymph nodes out of 74 were newly diagnosed as positive for metastasis only by the CUBIC-based screening (3D → sectioning), making the sensitivity of the routine diagnosis method 85.2% (23/27) with four false negative, i.e. 14.8% (4/27) improvement in sensitivity with CUBIC.