Figure 1 | Scientific Reports

Figure 1

From: Intravoxel incoherent motion diffusion-weighted imaging for discriminating the pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

Figure 1

A LARC patient from the pCR and GR groups (TRG 4). Images in the row A and B are T2WI, IVIM-DWI parametric and pathological maps before and after nCRT, respectively. The ADC, D, D* and f values before nCRT were 1.07 × 10−3 mm2/s, 0.785 × 10−3 mm2/s, 47.7 × 10−3 mm2/s and 0.206, respectively. The ADC, D, D*, and f values after nCRT were 2.28 × 10−3 mm2/s, 1.81 × 10−3 mm2/s, 55.5 × 10−3 mm2/s and 0.248, respectively. The pathological map (haematoxylin-eosin staining, original magnification x40) after nCRT indicates the absence of residual cancer (TRG 4). LARC, locally advanced rectal cancer; pCR, pathological complete response; GR, good response; TRG, tumour regression grade; T2WI, T2-weighted imaging; IVIM-DWI, intravoxel incoherent motion diffusion-weighted imaging; nCRT, neoadjuvant chemoradiotherapy; ADC, apparent diffusion coefficient; D, pure diffusion coefficient; D*, pseudo-diffusion coefficient; f, perfusion fraction.

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