Table 2 Linkage of the TOP1MT 256 and 525 alleles.

From: Distribution bias and biochemical characterization of TOP1MT single nucleotide variants

 

V256 homozygous

256 heterozygous

I256 homozygous

total

R525 homozygous

11

25

28

64

525 heterozygous

23

33

0

56

W525 homozygous

9

0

0

9

total

43

58

28

129

  1. *Source.
  2. 129 samples from women with breast cancers were used to genotype TOP1MT variants for both alleles at positions 256 (V or/and I) and 525 (R or/and W).
  3. Chi-square p value = 0.0005.
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