Table 3 Tissue-specific enrichment of the TOP1MT SNP variants in the NCI-60.

From: Distribution bias and biochemical characterization of TOP1MT single nucleotide variants

Cell line

Variant (dbSNP id)

V256I

R525W

rs11544484

rs2293925

LC:A549

42

0

LC:EKVX

97

0

LC:HOP_62

100

0

LC:HOP_92

0

0

LC:NCI_H226

100

0

LC:NCI_H23

0

0

LC:NCI_H322M

100

0

LC:NCI_H460

100

0

LC:NCI_H522

33

80

ME:LOXIMVI

0

0

ME:MALME_3 M

19

100

ME:M14

0

100

ME:SK_MEL_2

100

0

ME:SK_MEL_28

0

100

ME:SK_MEL_5

0

100

ME:UACC_257

31

0

ME:UACC_62

0

55

ME:MDA_MB_435

0

100

ME:MDA_N

0

96

  1. Numbers in both columns refer to the percentage of reads with that particular variant.