Figure 3

NK cell-activating receptors are upregulated by the combination of the αCD16 mAb with IrAPs. NK cell activation receptors were analyzed by flow cytometry (FCM). (A) Comparison of expression levels of NK cell receptors between days 0 and 21. (B,C) A representative FCM dot plot of resting NK cells (B) and NK cells expanded by the combination of the αCD16 mAb with IrAPs (C). The assay was conducted in triplicate for each donor (n = 5). The statistical significance was determined by one-way ANOVA. # P < 0.05, ## P < 0.005, ### P < 0.0005 (#NK alone versus other groups). *P < 0.05, **P < 0.005, ***P < 0.0005 (*NK + IrAPs versus other groups).