Figure 2 | Scientific Reports

Figure 2

From: Improved efficacy and in vivo cellular properties of human embryonic stem cell derivative in a preclinical model of bladder pain syndrome

Figure 2

M-MSC injection restored bladder function in HCl-IC model rats. (a) Representative awake cystometry results and (b) quantitative bladder voiding parameters at 1 week after the injection of M-MSCs (8 independent animals in each group) at the indicated dosage (K = a thousand). IVP; intravesical pressure, IAP; intra-abdominal pressure. Sham: sham-operated. (c) Quantitative data of bladder voiding parameters at 2 or 4 weeks after the injection of 1 × 106 M-MSCs (5 independent animals per group). All data are presented as the mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001 compared to the HCl-IC group; #p < 0.05, ##p < 0.001, ###p < 0.001 compared to the 1000 K group; $p < 0.05, $$p < 0.001, $$$p < 0.001 between 2 and 4 weeks group with Bonferroni post-test.

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