Table 2 5 top-ranked results for the frequency analysis for MC signatures.

From: Logic programming reveals alteration of key transcription factors in multiple myeloma

Predicted node

Sign

FS NPC

FS MC

p.val (Fisher)

References

Connectivity

OVE

+

−

JUN/FOS[n]

−

0.444

0.956

2.65E-005

38,39,40,41,42

8/529

373

137

FOXM1*[c]

−

0.222

0.774

7.97E-004

43, 44

529/529

85

265

STAT6*[c]

−

0.222

0.764

1.05E-003

∅

8/529

30

429

EGF/EGFR*[m]

+

0.556

0.935

2.08E-003

45,46,47

529/529

79

4

Src*

+

0.556

0.935

2.08E-003

48,49,50

529/529

110

48

  1. FS NPC and FS MC show the frequency scores for NPC and MC, respectively. The references column lists the publications that agreed with our sign prediction. Connectivity refers to the ratio of genes connected to each predicted node. The OVE (observed variant expression) shows the repartition of variant gene expression using the best precision threshold without considering graph information.
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