Figure 2 | Scientific Reports

Figure 2

From: MicroRNA-449c-5p inhibits osteogenic differentiation of human VICs through Smad4-mediated pathway

Figure 2

MiR-449c-5p is downregulated in human calcific aortic valves. (a) Heat map based on the differential expression of miRNAs between non-calcific and calcific aortic valves calculated by microarray. n = 3 in each group. (b) Verification of miR-449c-5p expression by qRT-PCR in non-calcific and calcific valves from 10 CAVD patients. Data are presented as the mean ± SD. *P < 0.05, **P < 0.01.

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