Figure 1 | Scientific Reports

Figure 1

From: Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer’s disease progression

Figure 1

Differentially expressed proteins in the OB across AD-related phenotypes. (a) Volcano plots representing the fold-change of identified proteins with associated P values from the pair-wise quantitative comparisons of control vs initial AD stage (upper panel), control vs intermediate AD stage (middle panel), and control vs advanced AD stage (lower panel). In green, very significantly changed proteins (P < 0.01), in yellow, significantly changed proteins (P < 0.05) and in blue, unchanged proteins between the pair-wise comparisons. (b) Differential olfactory proteome distribution across AD stages. (c) Venn diagram of common and unique differential proteins between AD stages. The distribution of common and distinct proteins in initial, intermediate, and advanced stages is shown.

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