Table 2 Alterations of the 18 key aminoacids for ornithine decarboxylase (the numbering of human ODC1 is used). Principal aminoacids involved in catalytic activity are indicated in bold. — = conserved aminoacids; § = missing data sequence.
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K69 | D88 | R154 | K169 | G171 | H197 | S200 | G235 | G236 | G237 | E274 | R277 | C360 | D361 | D364 | G387 | Y389 | F397 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SMED-ODC-A | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
DjODC2 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
DjODC1 | — | — | — | R | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
SMED-ODC-3 | — | — | — | — | — | — | N | — | — | — | — | T | — | — | — | — | — | — |
DjODC3 | — | — | — | — | — | — | N | — | — | — | — | T | — | — | — | — | — | — |
SMED-ODC-4 | — | — | — | — | — | — | I | — | — | — | T | — | — | — | — | — | — | — |
DjODC4 | — | — | — | — | — | — | I | — | — | — | T | — | — | — | — | — | — | — |
SMED-ODC-5 | — | — | — | — | — | — | — | — | — | — | — | A | V | — | — | — | — | — |
DjODC5 | — | — | — | — | — | — | — | — | — | — | — | A | § | § | § | § | § | § |
SMED-ODC-6 | S | S | A | — | A | F | T | — | D | — | Q | K | — | — | — | — | — | — |
DjODC6 | S | S | A | — | A | Y | T | — | D | — | Q | K | — | — | — | — | — | — |
