Table 4 Factor associated with P. falciparum seroprevalence among children ≤12 years old in four islands and a mainland village, Lake Victoria Kenya, 2012*.

From: Naturally acquired antibody response to Plasmodium falciparum describes heterogeneity in transmission on islands in Lake Victoria

Setting

Factor

AMA-1

MSP-119

CSP

aOR (95% CI)

P value

aOR (95% CI)

P value

aOR (95% CI)

P value

Ungoye

Age

1.21 (1.14–1.29)

<0.001

1.21 (1.14–1.28)

<0.001

—

—

Enlarged spleen

4.17 (2.81–6.20)

<0.001

2.30 (1.54–3.45)

<0.001

4.52 81.54–13.22)

0.006

Anaemia

—

—

1.88 (1.15–3.00)

0.012

—

—

Mfangano

Age

1.21 (1.15–1.27)

<0.001

—

—

—

—

Enlarged spleen

4.05 (2.95–5.53)

<0.001

1.84 (1.38–2.45)

<0.001

3.46 (1.93–5.79)

<0.001

Anaemia

—

—

1.47 (1.04–2.08)

0.03

—

—

Takawiri

Age

1.21 (1.13–1.29)

<0.001

—

—

—

—

Enlarged spleen

3.46 (2.07–5.78)

<0.001

2.04 (1.26–3.32)

0.004

4.31 (1.78–10.48)

0.001

Kibuogi

Age

1.25 (1.11–1.42)

<0.001

—

—

—

—

Enlarged spleen

2.80 (1.37–5.72)

0.005

—

—

—

—

Ngodhe

Age

1.34 (1.20–1.49)

<0.001

—

—

1.27 (1.03–1.57)

0.024

Enlarged spleen

—

—

5.11 (2.32–11.25)

<0.001

6.46 (1.95–21.38)

0.002

  1. *aOR, adjusted odd ratio; CI, confidence interval. Estimates are adjusted (i.e. age, gender, fever, anaemia and enlarged spleen) for correlation between observations from the same setting.
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