Figure 3 | Scientific Reports

Figure 3

From: Sost deficiency led to a greater cortical bone formation response to mechanical loading and altered gene expression

Figure 3

3D dynamic time lapsed in vivo morphometry of mineralizing volume (MV) and surface (MS) as well as eroded volume (EV) and surface (ES) at the tibial mid-diaphysis. All parameters are expressed as the amount of newly formed or resorbed bone between day 0 and day 15, normalized to the bone volume (BV) or bone surface (BS) at day 0, which includes both the periosteal and endocortical surfaces. ANOVA: indicates an effect of (a) genotype, (b) age, (c) loading, (d) genotype & age, (e) genotype & loading, (f) age & loading, p < 0.05. Asterisk indicates a significant difference between loaded and control tibiae (Paired t-test; p < 0.05).

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