Figure 2 | Scientific Reports

Figure 2

From: Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways

Figure 2

Effects of QE on liver function and pathology of C57 mice with liver fibrosis induced by BDL or CCl4. Notes: (A)The levels of serum ALT, AST and hydroxyproline content changed depending on the quercetin dose,100 mg/kg or 200 mg/kg. Data are given as means ± SD (n = 8, *P < 0.05 for sham or vehicle versus model group, #P < 0.05 for BDL(CCl4) + QE100 versus model groups, and +P < 0.05 for BDL(CCl4) + QE200 versus model groups). (B) Quercetin ameliorated pathologic changes caused by fibrotic progression, showed by H&E and Masson’s trichrome (original magnification, ×200).

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