Figure 3

Immune response genes are differentially regulated by WT and hrfΔ parasites. (A) mRNA levels (RT-qPCR) normalized to HPRT of cytokine production in spleen cells measured at different time points p.i., every other day from day 2 to day 14 p.i., from mice infected with 105 WT or PbNK65 hrfΔ iRBCs. (B) Determination of body weight measured over time during C57BL/6 mice infection. Error bars, SEM. Data are representative of two independent experiments with 5 mice per group. (*p < 0.03; Mann Whitney test).