Figure 6

Frequency of memory B cells in PbNK65-hrfΔ protected mice. Splenic B cells from naïve mice or 15 days p.i. with either WT or hrfΔ iRBCs were analysed fror their memory phenotype. Representative frequency and absolute number of AID/YFP⁺CD19⁺ (A), GC AID/YFP⁺CD19⁺ GL7⁺CD95⁺ (B) memory B cells. Representative frequency and absolute number, among GC B memory cell population, of IgM⁺IgG^- central memory B cells (C) or IgM⁻IgG⁺ effector memory B cells (D). Error bars, SEM. Data are representative of two independent experiments with 4 mice per group. (*p < 0.05; Mann Whitney test).