Figure 3 | Scientific Reports

Figure 3

From: Reduced basal forebrain atrophy progression in a randomized Donepezil trial in prodromal Alzheimer’s disease

Figure 3

Annualized Percentage Change (APC) of Basal forebrain cholinergic system subregions indicating a specific reduction of trophy after one year of treatment with Donepezil in the Necleus Basalis of Mynert and in the medial septum and the vertical limb of the diagonal band of Broca. Least squares means and 95% Confidence Interval are reported, p-values denote significant differences between treatment groups at General Linear Model including age, gender, MRI field strength (1.5 T or 3 T) and MRI scanner manufacturer (Philips, GE Healthcare or Siemens) as covariates. NbM = Nucleus Basalis of Meynert; Ch4p = posterior Nucleus Basalis Meynert (NBM); Ch1/2 = combined clusters of the medial septum and the vertical limb of the diagonal band of Broca.

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