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Figure 1

From: Hypoxic Stress Decreases c-Myc Protein Stability in Cardiac Progenitor Cells Inducing Quiescence and Compromising Their Proliferative and Vasculogenic Potential

Figure 1

Hypoxic stress reduces cardiac progenitor cell proliferation. (A) Time-course analysis of CPC growth represented by number of cells (top panel) and population doubling (lower panel) under normoxia (closed circles) and hypoxia (open circles) over a total period of 96 hours (n = 7, *p < 0.05). (B) Quantitative analysis of Ki67 positive cells after exposure of CPCs to hypoxia by fluorescence activated cell sorting. Representative images under normoxia and hypoxia from 48–96 hours are shown. Graph indicates the average percentage of Ki67 positive cells under normoxia (black bars) and hypoxia (gray bars) at different time points (n = 3, *p < 0.05, ** < 0.005).

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