Figure 2

PLD2 ^−/− mice are neither obese nor hyperlipidemic. (A) weight at 5 months, n = 7 mice of each genotype. LDL (B), HDL (C), and total serum cholesterol/HDL ratio (D) after 0, 3 and 7 months on a high fat diet (n = 3 mice of each genotype). Mean ± SEM; **p < 0.01; ***p ≤ 0.001 (Student’s t-test).