Figure 4 | Scientific Reports

Figure 4

From: A missense MT-ND5 mutation in differentiated Parkinson Disease cytoplasmic hybrid induces ROS-dependent DNA Damage Response amplified by DROSHA

Figure 4

Differentiated PD63 cybrid cells have increased levels of ROS. (A) ROS detection (green) with CellROX Green Reagent kit (Invitrogen™). Phase contrast images (60X) of the same fields are also shown. (B) Western blot analysis of γH2AX in differentiated PD63 cells grown in the presence of N-acetyl-cysteine (NAC) or N-acetyl-alanine (NAA) as control. GAPDH, loading control.

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