Figure 3
From: Population mechanics: A mathematical framework to study T cell homeostasis
Dynamics of memory T cell clones according to equation (6). (A) The activation of a clone of naïve T cells entails a transitory increase in the number of memory T cells. The existence of a carrying capacity forces the population back to equilibrium and, in this process, a clone initially containing m 2,0 cells shrinks to a new size denoted by \({m}_{2}^{\ast }\). The number of new memory T cells goes from an initial value of m 1,0 to \({m}_{1}^{\ast }\) at equilibrium. (B) A similar dynamics takes place after reactivation of a clone of memory T cells. Reactivation causes an initial change in the number of cells of the clone (denoted by Δm 1), which modifies the size of pre-existing memory clones.
