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Figure 1

From: Structural and Functional View of Polypharmacology

Figure 1

Proportion of drug-binding proteins in CATH-FunFams and the druggable genome. (A) Proportion of drug-binding proteins in 195 selected CATH-FunFams. FunFams were selected for having at least one drug-binding protein amongst their relatives and containing more than 2% of drug targets. (B) Slopegraph comparing the previous distribution of druggable protein families (i.e. the druggable genome) by Hopkins and Groom20 and our distribution of druggable CATH-FunFams.

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